两种立方体构型的微泡超声造影剂的温度场

doi:10.3969/j.issn.1007-2861.2015.02.014

Journal of Shanghai University（Natural Science Edition） ›› 2016, Vol. 22 ›› Issue (5): 616-623.doi: 10.3969/j.issn.1007-2861.2015.02.014

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Temperature field of microbubble ultrasonic contrast agent in cube and closely-packed cube configurations

YANG Qing1, XU Kaiyu1,2, FENG Jiangtao1,2

1. Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai 200072, China;
2. College of Sciences, Shanghai University, Shanghai 200444, China

Received:2015-04-12 Online:2016-10-31 Published:2016-10-31

Abstract

Abstract:

This paper studies the temperature field in blood by calculating viscous energy dissipation of phospholipid membrane based ultrasonic contrast agent under the sound pressure excitation. According to the experimental observation, a cube model with a red blood cell as center and eight microbubbles as vertices is proposed. Temperature rise of the center is also calculated. Furthermore, considering the condition of high microbubble concentration and its adhesion to the surface of organizations, a cube model of closelypacked structure is also built. Temperature field in a rectangular region and the peak temperature is obtained though this model. Safety is analyzed in detail to demonstrate feasibility and effectiveness of the proposed model.

Key words: closely-packed cube model, cube model , dissipated energy , temperature field , ultrasonic contrast agent

YANG Qing1, XU Kaiyu1,2, FENG Jiangtao1,2. Temperature field of microbubble ultrasonic contrast agent in cube and closely-packed cube configurations[J]. Journal of Shanghai University（Natural Science Edition）, 2016, 22(5): 616-623.

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Temperature field of microbubble ultrasonic contrast agent in cube and closely-packed cube configurations

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