The rapid developments of aeronautic and aerospace, shipping, automobile and power generating equipment manufacturing create urgent requirements of China’s research and development capability in advanced grinding machines. Among the statefunded major projects for producing highend digitalcontrolled machine tools and key manufacturing equipment, two tasks have been undertaken by Shanghai University. One is to develop a whole set of highprecision grinding machines for ball screw and nut, and the other is a largescale computer numerical control (CNC) tangential point tracing grinding machine for the crankshaft used in marine diesel engine. Both the strong support of common techniques and the perfect mastery of key techniques make the advanced grinding machines developed rapidly. Based on practice, some of thoughts on the technical strategy for attacking major difficulties are provided and suggestions on the development of advanced grinding machines in order to promote academic exchanges are presented.