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Journal of Shanghai University >

2011 , Vol. 17 >Issue 3: 302 - 306

DOI: https://doi.org/doi:10.3969/j.issn.1007-2861.2011.03.018

Environmental and Chemical Engineering

Effect of Polyethylene Glycol Multiwalled Carbon Nanotubes to Plasmid DNA

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  • 1. Beiyuan Campus, Beijing Union University, Beijing 100012, China;
    2. School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China

Received date: 2011-02-08

  Online published: 2011-06-24

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Abstract

The biocompatibility of pristine multiwalled carbon nanotubes (MWNTs), purified MWNTs and polyethylene glycol MWNTs (PEGMWNTs) was studied using the method of plasmid DNA assay and atomic force microscopy (AFM). The results show that pristine MWNTs can cause serious damage to plasmid DNA. After purification, MWNTs may cause less damage to plasmid DNA, while at the same concentration level, PEGMWNTs cause the smallest damage to plasmid DNA.

Key words： biosafety; DNA; multi-walled carbon nanotubes (MWNTs)

Cite this article

LAO Wen-Yan, SHANG Ying-Hui, JIAO Zheng, LAO Feng-Xue . Effect of Polyethylene Glycol Multiwalled Carbon Nanotubes to Plasmid DNA[J]. Journal of Shanghai University, 2011 , 17(3) : 302 -306 . DOI: doi:10.3969/j.issn.1007-2861.2011.03.018

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