Journal of Shanghai University(Natural Science Edition) ›› 2010, Vol. 16 ›› Issue (3): 281-285.

• Mathematics.Physics and Chemistry • Previous Articles     Next Articles

Computational Prediction of Protein-DNA Interaction Based on Wavelet Transform

JIANG Hao,FENG Tie-nan,QIN Dian-gang,WANG Yi-fei   

  1. (College of Sciences, Shanghai University, Shanghai 200444, China)
  • Online:2010-06-28 Published:2010-06-28

Abstract:

Protein-DNA interactions are vital for many processes such as transcriptional regulation and DNA modification in living cells. This paper uses the modified resonant recognitions model to predict interactions between yeast proteins and DNA. The difference of distributions of signal-to-noise ratio (SNR) between the positive data and the random data are found using wavelet transform. Satisfactory results are obtained by choosing an appropriate threshold.

Key words: resonant recognition model; discrete wavelet transform; protein-DNA interaction; signal-to-noise ratio (SNR)