Abstract:

Interaction between salidroside and β-cyclodextrin（β-CD） was studied with UV spectrometry based on the fact that the absorption peak position of salidroside is kept unchanged but the absorbance increased with the increase of β-CD concentration. The formation constants of the inclusion complexes are determined and effects of temperature on equilibrium constants examined, from which the thermodynamic parameters were calculated, and driving forces of formation of inclusion complex are discussed. The results imply that complexation is enthalpically and entropically favourable and driven mainly by hydrophobic interaction.

Key words: salidroside; UV spectrometry; β-cyclodextrin (β-CD); formation constant of inclusion complex