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Journal of Shanghai University（Natural Science Edition） ›› 2011, Vol. 17 ›› Issue (4): 458-470.doi: 10.3969/j.issn.1007-2861.2011.04.013

• Mathematics.Physics and Chemistry • Previous Articles     Next Articles

Design and Synthesis of Fluorine-Containing Building Blocks and Application to Synthesis of Fluorinated Heterocycles

JIANG Hai-zhen1,SONG Li-ping1,2,LUO Hui-hua1,YI Hai1,ZHU Shi-zheng2,HAO Jian1,2   

  1. 1. College of Sciences, Shanghai University, Shanghai 200444, China; 2. Key Laboratory of Organofluorine Chemistry, Chinese Academy of Sciences, Shanghai 200032, China
  • Received:2011-06-30 Online:2011-08-30 Published:2011-08-30

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Abstract: Fluorinated heterocycles have attracted substantial research attention in the fields of medicine, pesticide and special-function materials, which have special properties caused by fluorine atoms. This review highlights the recent development on the synthesis of novel fluorine-containing building blocks, such as fluorine-containing keto esters and fluorine-containing imidoyl halides, and on their applications to the preparation of fluorinated heterocycles.

Key words: fluorinated heterocycle, fluorine-containing building block, imidoyl halide, keto ester

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