发酵乳杆菌 B44 益生性能的体外评价

doi:10.12066/j.issn.1007-2861.2207

Abstract

Abstract:

Lactobacillus fermentum B44 is a lactic acid strain isolated from Bulgarian homemade yoghurt. In vitro experiments showed that L. fermentum B44 has strong hydrophobicity (79.67%) and an electrostatic effect of low acid and high alkali; the strain could tolerate 1 mg/mL lysozyme and has a better adhesion and survival ability in oral cavities. In addition, it also has a high self-agglomeration rate (13.34%) and strong co-aggregation with Streptococcus mutans. When co-cultured with S. mutans, the formation of S. mutans biofilm was inhibited, and the inhibition rate was 63.43%. The above results showed that L. fermentum B44 could play a positive role in preventing and treating human dental caries; it is a potential oral probiotic and has a suitable application prospect in human oral health.

Key words: probiotics, Streptococcus mutans, biofilm, caries disease, co-aggregation

CLC Number:

HAN Jin, WU Yanting, WAN Sibao, WU Zhengjun. In vitro evaluation of the prebiotic properties for Lactobacillus fermentum B44[J]. Journal of Shanghai University（Natural Science Edition）, 2021, 27(6): 1162-1170.

Figures/Tables 6

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In vitro evaluation of the prebiotic properties for Lactobacillus fermentum B44

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