不同种类的ZnO纳米颗粒对人胃黏膜上皮细胞离子吸收的影响

doi:10.12066/j.issn.1007-2861.2170

Abstract

Abstract:

This paper systematically studied the effects of different types and low concentrations of ZnO nanoparticles (NPs) on the uptake of Fe$^{3+}$, Ca$^{2+}$ and Mg$^{2+}$ in human gastric epithelium cells-1 (GES-1). The results showed that ZnO NPs had the most significant impact on the absorption of Fe$^{3+}$. The changes in the three ion concentrations in GES-1 were related to the size and concentration of ZnO NPs. Among them, the effect of 50 nm ZnO NPs on the absorption of ions was the most significant, reaching the highest concentration at 15 mg/L. However, the hydrophilic and lipophilic properties of ZnO NPs had no obvious effect on the absorption of ions. Finally, the mechanism of ion adsorption was discussed by detecting the cell viability and reactive oxygen species (ROS) levels of different types of ZnO NPs.

Key words: ZnO nanoparticles (NPs), size, concentration, ion absorption

CLC Number:

Q256

WANG Mimi, WU Minghong, WANG Yanli. Effects of different ZnO nanoparticles on ion absorption in human gastric epithelium cells[J]. Journal of Shanghai University（Natural Science Edition）, 2021, 27(4): 696-705.

Figures/Tables 7

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References 19

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Effects of different ZnO nanoparticles on ion absorption in human gastric epithelium cells

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