Journal of Shanghai University(Natural Science Edition) ›› 2019, Vol. 25 ›› Issue (5): 767-775.doi: 10.12066/j.issn.1007-2861.1961

• Research Paper • Previous Articles     Next Articles

Properties of a new magnetic biological patch

Kai YANG, Ning PEI(), Qixin WANG, Lanlan CAI   

  1. College of Sciences, Shanghai University, Shanghai 200444, China
  • Received:2017-06-05 Online:2019-10-30 Published:2019-10-31
  • Contact: Ning PEI E-mail:pn@shu.edu.cn

Abstract:

A new non-toxic magnetic biological patch had been designed for implant assisted-magnetic drug targeting. The structure and properties of the MBP were characterized. In vitro experimental results showed that the ferric oxide particles could be captured effectively around MBP when it was placed in the uniform magnetic field. Effects of the distance between fluid and MBP, and magnetic flux density on the accumulation of the ferric oxide particles attracted by MBP were investigated in vitro. Accumulation of ferric oxide particles decreased rapidly with the increasing distance between fluid and MBP. Accumulation of ferric oxide particles first increased and then decreased with increment of magnetic flux density of the uniform magnetic field. Experiment results were explained by numerical analysis using Software Ansys.

Key words: magnetic targeting, finite-element analysis, magnetic biological patch, magnetic flux density

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