数理化科学

一类具有病菌信息交流机制的时滞模型的稳定性

展开
  • 1. 西安科技大学 理学院, 西安 710054; 2. 上海大学 上海市应用数学和力学研究所, 上海 200072

收稿日期: 2012-12-26

  网络出版日期: 2013-06-30

基金资助

国家自然科学基金资助项目(11201277, 10971064, 11271125); 中国博士后基金资助项目(20090461281); 陕西省教育厅专项科研计划基金资助项目(09JK601, 12JK0581, 2013JK0611); 信阳师范学院种群生态模拟与控制重点试验室开放课题基金资助项目(201004)

Stability of a Delayed Model with the Mechanism of Information Exchange

Expand
  • 1. School of Sciences, Xi’an University of Science and Technology, Xi’an 710054, China; 2. Shanghai Institute of Applied Mathematics and Mechanics, Shanghai University, Shanghai 200072, China

Received date: 2012-12-26

  Online published: 2013-06-30

摘要

考虑病菌的群体感应机理建立了一类人体免疫细胞与病菌竞争的时滞微观动力学模型, 并综合运用Liapunov 稳定性理论、中心流形定理及规范型理论等, 讨论了无菌平衡点的局部及全局渐近稳定性, 正平衡点的存在性、全局渐近稳定性无菌平衡点在奇异条件下的稳定性.

本文引用格式

张仲华1, 孟庆勋2, 锁要红1 . 一类具有病菌信息交流机制的时滞模型的稳定性[J]. 上海大学学报(自然科学版), 2013 , 19(3) : 308 -314 . DOI: 10.3969/j.issn.1007-2861.2013.03.017

Abstract

To characterize the competition between immune cells and bacteria, a microcosmic dynamical model with delayed quorum sensing mechanism is constructed. According to the Liapunov staiblity theory, the center manifold theorem and the norm form theory, local and global stability of the bacteria free equilibrium, existence and globally asymptotical stability of the positive equilibrium, and stability of the nonhyperbolic bacteria free equilibrium are studied for any positive delay.

参考文献

[1] Healson K H, Platt T, Hastings J W. Cellular control of the syntesis and activity of the bacterial luminescent system [J]. J Bacteriol, 1970, 104(1): 313-322.

[2] Fuqua W C, Winans S C, Greenberg E P. Quorum sensing in bacteria: the LuxR-Luxl family of cell density-responsive transcriptional regulations [J]. J Bacteriol, 1994, 176(2): 269-275.

[3] 吴红, 宋志军, Niels H, 等. 细菌与细菌之间的信息交流—革兰氏阴性细菌的Quorum-sensing 系统[J]. 自然科学进展, 2003, 13(7): 679-687.

[4] Zhang Z H, Peng J G, Zhang J. Analysis of a bacteria-immunity model with delay quorum sensing [J]. J Math Appl Anal, 2008, 340(1): 102-115.

[5] Song Y, Han M, Wei J. Stability and Hopf bifurcation on a simplified BAM neural network with delays [J]. Physica D, 2005, 200(3/4): 85-204.

[6] Kuang Y. Delay differential equations with applications in population dynamics [M]. New York: Academic Press, 1993.

[7] Hale J K, Verduyn-Lunel S M. Introduction to functional differential equations [M]. New York: Springer Verlag, 1993.

[8] Faria T, Magalhaes L T. Normal forms for retarded differential equations and applications to Bogdanov-Takens singularity [J]. J Diff Equations, 1995, 122(2): 201-224.
文章导航

/