基于薄膜晶体管的冠状病毒检测研究进展

doi:10.12066/j.issn.1007-2861.2596

上海大学学报(自然科学版) ›› 2024, Vol. 30 ›› Issue (6): 989-1005.doi: 10.12066/j.issn.1007-2861.2596

• • 下一篇

基于薄膜晶体管的冠状病毒检测研究进展

涂建新, 郝魁, 孙乐, 李爱军

1. 上海大学材料科学与工程学院, 上海 200444; 2. 上海大学绍兴研究院, 浙江绍兴 312000

收稿日期:2024-05-14 出版日期:2024-12-28 发布日期:2025-01-02
通讯作者: 李爱军 (1975—), 男, 教授, 博士生导师, 博士, 研究方向为半导体纳米材料与器件等. E-mail:aijun.li@shu.edu.cn
基金资助:
上海市自然科学基金资助项目 (20ZR1419600)

Research progress in coronavirus detection based on thin-film transistors

TU Jianxin, HAO Kui , SUN Le , LI Aijun

1. School of Materials Science and Engineering, Shanghai University, Shanghai 200444, China; 2. Shaoxing Institute of Technology, Shanghai University, Shaoxing 312000, Zhejiang, China

Received:2024-05-14 Online:2024-12-28 Published:2025-01-02

摘要/Abstract

摘要： 薄膜晶体管 (thin-film transistors, TFTs) 已广泛应用于生物电子学领域, 用来检测代谢物、核酸、蛋白质、细胞活动和电生理信号. 在新冠病毒大流行期间, 基于 TFTs 的 COVID-19 生物传感器展现出良好的性能和高应用潜力. 石墨烯场效应晶体管 (graphene field-effect transistors, GFETs)、氧化物薄膜晶体管、有机场效应晶体管 (organic field-effect transistors, OFETs) 和有机电化学晶体管 (organic electrochemical transistors, OECTs) 等薄膜晶体管在病毒、RNA、抗原、抗体的检测中均取得了良好的结果. 总结了基于薄膜晶体管的新冠病毒和相关生物标志物检测的生物传感器, 讨论了基于不同沟道材料晶体管的传感策略. 最后, 对未来薄膜晶体管应用于病毒检测的研究方向提出展望.

关键词: 薄膜晶体管, 生物传感器, 冠状病毒检测, 有机电化学晶体管, 有机场效应晶体管

Abstract: Thin-film transistors (TFTs) are widely used in bioelectronics for application in detecting metabolites, nucleic acids, proteins, cellular activities, and electrophysiological signals. During the COVID-19 pandemic, TFT-based COVID-19 biosensors displayed excellent performances and high levels of potential for use in various applications. TFTs, such as oxide-based TFTs and graphene field-effect, organic field-effect, and organic electrochemical transistors, yielded promising results in detecting viruses, ribonucleic acid, and antigens and antibodies. This review summarizes biosensors based on TFTs for use in detecting SARS-CoV-2 and the related biomarkers and analyzes sensing strategies based on transistors with different channel materials. Finally, future directions for researches regarding the applications of TFTs in viral detection are proposed.

Key words: thin-film transistors, biosensors, corona virus detection, organic electrochemical transistors, organic field-effect transistors

中图分类号:

Q 5-3

涂建新, 郝魁, 孙乐, 李爱军. 基于薄膜晶体管的冠状病毒检测研究进展[J]. 上海大学学报(自然科学版), 2024, 30(6): 989-1005.

TU Jianxin, HAO Kui , SUN Le , LI Aijun. Research progress in coronavirus detection based on thin-film transistors[J]. Journal of Shanghai University（Natural Science Edition）, 2024, 30(6): 989-1005.

基于薄膜晶体管的冠状病毒检测研究进展

Research progress in coronavirus detection based on thin-film transistors

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 0

编辑推荐

Metrics

本文评价