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Induced pluripotent stem cells in cardiac regeneration
Received date: 2016-04-22
Online published: 2016-06-30
Induced pluripotent stem cells (iPSCs) have emerged as a novel tool for cell therapy for cardiovascular diseases. iPSCs are functionally similar to embryonic stem cells (ESCs) while avoiding ethical issues and immune rejection. Given limited regenerative ability of human heart following cardiovascular diseases cardiovascular cells derived from iPSCs have been considered as a promising cell source in cardiovascular regenerative therapy. This paper summarizes and discusses the iPSCs technology and its potential regenerative applications in cardiac regeneration.
HU Shijun1,2, YU You1,2, FANG Xing1,2, LEI Wei1,2, ZHAO Zhen’ao1,2 . Induced pluripotent stem cells in cardiac regeneration[J]. Journal of Shanghai University, 2016 , 22(3) : 285 -292 . DOI: 10.3969/j.issn.1007-2861.2016.04.001
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