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Journal of Shanghai University >

2015 , Vol. 21 >Issue 1: 54 - 63

DOI: https://doi.org/10.3969/j.issn.1007-2861.2014.03.004

Metallurgical Materials

Template preparation of Ag nanoparticle arrays SERS-active substrate and highly sensitive detection of glucose

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  • 1. School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444, China; 2. Instrumental Analysis & Research Center, Shanghai University, Shanghai 200444, China

Received date: 2014-03-05

  Online published: 2015-02-28

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Abstract

A highly sensitive method for detecting glucose using Ag nanoparticle arrays surface-enhanced Raman scattering (SERS) active substrates based on the ultra-thin alumina mask (UTAM) was reported. The large-area highly ordered Ag nanoparticle arrays active substrates were fabricated using thermal evaporation with UTAM as a shadow mask in vacuum. The surface of active substrates can adsorb a layer of decanethiol/mercaptohexanol (DT/MH) self-assembled monolayers (SAM) through the surface pretreatment. Therefore the active substrates can be used for detecting glucose molecules. SERS measurement results of the active substrate with glucose molecules as probe molecules show strong SERS performance, and the enhanced signal is uniform and stable. The relative standard deviation (RSD) of the characteristic peak intensity is less than 10%. This preparation method has the advantages of simple operation and low cost.

Key words： glucose; nanoparticle; physiological concentration; surface-enhanced Raman scattering (SERS); ultra-thin alumina mask (UTAM)

Cite this article

GUO He-shuai1, FU Qun1, LIN Wei1, ZHENG Xian-zheng1, LU Bo2, WU Ming-hong1, LEI Yong1 . Template preparation of Ag nanoparticle arrays SERS-active substrate and highly sensitive detection of glucose[J]. Journal of Shanghai University, 2015 , 21(1) : 54 -63 . DOI: 10.3969/j.issn.1007-2861.2014.03.004

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