Life Science

Effects of Exposure to Ultra High Static Magnetic Fields on Antioxidation and Immune Functions of Mice

Expand
  • School of Life Sciences, Shanghai University, Shanghai 200444, China

Received date: 2011-02-23

  Online published: 2012-12-28

Abstract

Study the effects of exposure to ultra high static magnetic fields on antioxidation and immune functions of mice. Four-week old mice were exposed to the static magnetic fields with magnetic intensity of 12 Tesla (T) for 2 hours every day, and continued for 7 days. On the ninth day, the mice were sacrificed. Livers and kidneys were taken to measure the activity of Catalase (CAT), Superoxide Dismutase (SOD), Total antioxidant capacity (T-AOC), Glutathione peroxidase (GSH-Px) and the content of Maleic Dialdehyde (MDA). Also, thymus and spleen were obtained to measure their index and the splenic lymphocyte proliferation. Besides, blood of mice was collected by taking the eyeball and the content of white cells in the peripheral blood of mice was detected. Compared to control group, activity of CAT, SOD, T-AOC and GSH-Px in kidney in the experiment group were increased significantly. The content of MDA was decreased significantly. Activity of SOD and GSH-Px in liver was enhanced, and the content of MDA decreased significantly. Furthermore, splenic lymphocyte proliferation was increased, and the index of thymus and the content of white cells in peripheral blood were increased remarkably. Exposure to ultra high static magnetic fields can improve antioxidation and immune functions of mice.

Cite this article

HONG Xiao-tong, LIAO Xian-yan, WENG Xin-chu . Effects of Exposure to Ultra High Static Magnetic Fields on Antioxidation and Immune Functions of Mice[J]. Journal of Shanghai University, 2012 , 18(6) : 651 -655 . DOI: 10.3969/j.issn.1007-2861.2012.06.019

References

[1]FEYCHTING  M. Health effects of static magnetic fields-a review of the epidemiological evidence [J]. Progress in Biophysics and Molecular Biology, 2005, 87(2-3):241-246.

[2]MCKINLAY  A F, REPACHOLI M H. More research is needed to determine the safety of static magnetic fields [J].Progress in Biophysics and Molecular Biology, 2005, 87(2-3):173-174.

[3]FEYCHTING  M, AHLBOM A, KHEIFETS L. EMF and health [J]. Annual Review of Public Health, 2005, 26(1):165-189.

[4]HARDELL  L, SAGE C. Biological effects from electromagnetic field exposure and public exposure standards [J]. Biomedicine and Pharmacotherapy, 2008, 62(2):104-109.

[5]TUROWSKI  G, SESHADRI M, LOECHER M, et al. Performance of a novel piezoelectric motor at 4.7 T: applications and initial tests [J]. Magnetic Resonance Imaging, 2008, 26(3):426-432.

[6]HASHISH  A H, EL-MISSIRYL M A, ABDELKADER H I, et al. Assessment of biological changes of continuous whole body exposure to static magnetic field and extremely low frequency electromagnetic fields in mice [J]. Ecotoxicology and Environmental Safety, 2008, 71(3):895-902.

[7]MIYAKOSHI  J. The review of cellular effects of a static magnetic field [J]. Science and Technology of Advanced Materials, 2006, 7(4):305-307.

[8]张璐,王沂,胡俊,等.超强静磁场对小鼠抗氧化和免疫功能的影响[J].上海大学学报:自然科学版,2009,15(2):211-215.

[9]李晓林,李晓梅,陆艳娟,等.恒定磁场抗衰老作用的实验研究[J].中华物理医学与康复杂志,2005,27(1):13-14.

[10] 吴全义,刘方平,马洁,等.稳恒磁场对小鼠肾脏组织GSH-Px活性及MDA含量的影响[J].中国老年学杂志,2004,8(24):729-730.

[11] 郭红梅,成月明,潘翠燕,等.恒定磁场对小鼠免疫功能的影响[J].生物磁学,2005,5(4):18-19.

[12] 区炳庆,赵海全,何丽烂.多粘菌素对雏鸭血液中超氧化物歧化酶活性及丙二醛含量的影响[J].中国兽医科技,2003,33(1):50-52.

[13] 关微华,马波,朱翔.恒磁场对人鼠血液流变学及一氧化氮含量的影响[J].中国医学物理学杂志,2003,20(2):122-123.

[14] 付梅.生物磁现象和磁效应及其应用[J].现代物理知识,2004,16(1):15-16.

[15] 潘建平,邵传森.医学免疫学[M].浙江:浙江大学出版社,2006.

[16] 朱杰.磁场的生物学效应及其机理的研究[J].生物磁学,2005,5(1):26-29.
Outlines

/