With the development of computer simulation technology, digital production line logistics system receives increasingly more attention. Bottlenecks in a production line can be found in logistics simulation to avoid risk in the investment and construction. Logistics simulation is performed with the software Quest to achieve system optimization. The aim of simulation is to find bottlenecks in a production line and identify causes of the problem. The system configuration is optimized to meet certain optimization goals. Statistical parameters before and after configuration are compared to obtain an optimal solution.