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Journal of Shanghai University >

2022 , Vol. 28 >Issue 6: 1063 - 1068

DOI: https://doi.org/10.12066/j.issn.1007-2861.2315

Research Articles

Research progress on the relationship between blood brain barrier and central nervous system diseases

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  • Department of Neurology, The Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang, China

Received date: 2021-04-02

  Online published: 2021-06-11

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Abstract

The central nervous system receives the input information from all parts of the body, and becomes a coordinated motor outflow after the integration and processing of the central nervous system, or stored in the central nervous system to become the neural basis of learning and memory. Central nervous system is easy to be affected by pathogenic factors, and the main manifestation is mental disorders. At the same time, central nervous system degeneration can also occur. The blood-brain barrier can make the brain tissue less or even not damaged by harmful substances in the circulating blood, thus maintaining the basic stability of the brain tissue, which has important biological significance for maintaining the normal physiological state of the central nervous system. This paper summarizes and reviews the research progress of the relationship between blood-brain barrier and central nervous system diseases, in order to provide a new and more comprehensive theoretical basis for the prevention and treatment of central nervous system diseases.

Key words： central nervous system (CNS) diseases; blood brain barrier; brain tissue

Cite this article

SONG Ling, ZHAO Linlin, GUO Siqi, LI Huiling, ZHANG Jingyu . Research progress on the relationship between blood brain barrier and central nervous system diseases[J]. Journal of Shanghai University, 2022 , 28(6) : 1063 -1068 . DOI: 10.12066/j.issn.1007-2861.2315

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