Journal of Shanghai University(Natural Science Edition) ›› 2024, Vol. 30 ›› Issue (6): 989-1005.doi: 10.12066/j.issn.1007-2861.2596

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Research progress in coronavirus detection based on thin-film transistors

TU Jianxin, HAO Kui , SUN Le , LI Aijun   

  1. 1. School of Materials Science and Engineering, Shanghai University, Shanghai 200444, China; 2. Shaoxing Institute of Technology, Shanghai University, Shaoxing 312000, Zhejiang, China
  • Received:2024-05-14 Online:2024-12-28 Published:2025-01-02

Abstract: Thin-film transistors (TFTs) are widely used in bioelectronics for application in detecting metabolites, nucleic acids, proteins, cellular activities, and electrophysiological signals. During the COVID-19 pandemic, TFT-based COVID-19 biosensors displayed excellent performances and high levels of potential for use in various applications. TFTs, such as oxide-based TFTs and graphene field-effect, organic field-effect, and organic electrochemical transistors, yielded promising results in detecting viruses, ribonucleic acid, and antigens and antibodies. This review summarizes biosensors based on TFTs for use in detecting SARS-CoV-2 and the related biomarkers and analyzes sensing strategies based on transistors with different channel materials. Finally, future directions for researches regarding the applications of TFTs in viral detection are proposed.

Key words: thin-film transistors, biosensors, corona virus detection, organic electrochemical transistors, organic field-effect transistors

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