收稿日期: 2015-04-12
网络出版日期: 2016-10-31
基金资助
国家杰出青年科学基金资助项目(11102105); 上海市自然科学基金资助项目(15ZR1416100)
Temperature field of microbubble ultrasonic contrast agent in cube and closely-packed cube configurations
Received date: 2015-04-12
Online published: 2016-10-31
杨青1, 徐凯宇1,2, 冯江涛1,2 . 两种立方体构型的微泡超声造影剂的温度场[J]. 上海大学学报(自然科学版), 2016 , 22(5) : 616 -623 . DOI: 10.3969/j.issn.1007-2861.2015.02.014
This paper studies the temperature field in blood by calculating viscous energy dissipation of phospholipid membrane based ultrasonic contrast agent under the sound pressure excitation. According to the experimental observation, a cube model with a red blood cell as center and eight microbubbles as vertices is proposed. Temperature rise of the center is also calculated. Furthermore, considering the condition of high microbubble concentration and its adhesion to the surface of organizations, a cube model of closelypacked structure is also built. Temperature field in a rectangular region and the peak temperature is obtained though this model. Safety is analyzed in detail to demonstrate feasibility and effectiveness of the proposed model.
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