环境雌激素(environmental estrogens, EEs)已成为环境领域的热点问题, 其中壬基酚(nonylphenol, NP)和双酚A(bisphenol A, BPA)因广泛存在于水生环境中, 对水生生物特别是鱼类造成了潜在的危害而备受关注. 但是,NP 和BPA 在水体中的浓度不高, 难以对它们进行准确的测定. 鱼体胆汁具有较高的生物蓄积性, 可以通过鱼类胆汁来对污染物质进行测定, 从而反映水体的污染状况. 本工作主要从预处理(水解和固相萃取)和检测分析(色谱和质谱联用技术)两方面展开, 介绍了鱼体胆汁中NP 和BPA 的分析方法, 并比较了不同处理、分析方法的灵敏度和优缺点, 为建立NP 和BPA 等EEs 类物质在水生生物样品中的检测方法提供参考.
关键词：
胆汁; 环境检测; 壬基酚; 双酚A; 鱼
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