收稿日期: 2021-04-02
网络出版日期: 2021-06-11
基金资助
外泌体对脑缺血再灌注损伤的作用及机制研究(2020-12)
Research progress on the relationship between blood brain barrier and central nervous system diseases
Received date: 2021-04-02
Online published: 2021-06-11
宋岭, 赵琳琳, 郭思琦, 李慧灵, 张惊宇 . 血脑屏障和中枢神经系统疾病相关性的研究进展[J]. 上海大学学报(自然科学版), 2022 , 28(6) : 1063 -1068 . DOI: 10.12066/j.issn.1007-2861.2315
The central nervous system receives the input information from all parts of the body, and becomes a coordinated motor outflow after the integration and processing of the central nervous system, or stored in the central nervous system to become the neural basis of learning and memory. Central nervous system is easy to be affected by pathogenic factors, and the main manifestation is mental disorders. At the same time, central nervous system degeneration can also occur. The blood-brain barrier can make the brain tissue less or even not damaged by harmful substances in the circulating blood, thus maintaining the basic stability of the brain tissue, which has important biological significance for maintaining the normal physiological state of the central nervous system. This paper summarizes and reviews the research progress of the relationship between blood-brain barrier and central nervous system diseases, in order to provide a new and more comprehensive theoretical basis for the prevention and treatment of central nervous system diseases.
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