收稿日期: 2017-04-24
网络出版日期: 2019-12-31
基金资助
国家自然科学基金资助项目(11675098);国家自然科学基金资助项目(41373098);国家自然科学基金资助项目(41430644);国家自然科学基金资助项目(41473090)
Degradation behavior of antidepressant amitriptyline under electron beam irradiation
Received date: 2017-04-24
Online published: 2019-12-31
药物污染物已成为环境中的新兴污染物, 抗抑郁药物污染物是其中重要的组成部分. 这类污染物对于环境有潜在的威胁, 且现有的污水处理技术难以有效降解. 研究将电子束辐照技术应用于抗抑郁药阿米替林(amitriptyline, AMI)的降解, 模拟了 AMI 在真实水环境中的降解, 各种影响条件包括初始浓度、辐照剂量、pH、H$_{2}$O$_{2}$量、气氛条件、离子对降解的影响, 并根据产物分析推断了可能的降解路径. 结果表明, 上述因素对 AMI 的辐照降解有重要影响, 目标物的降解遵循假一级动力学方程, 在辐照剂量为 5 kGy 时, 目标污染物得到完全降解. 电子束辐照技术是处理 AMI 污染物的良好方式.
邓飞, 李旭, 袁得宝, 赵涛, 毛雯, 吴明红, 徐刚 . 抗抑郁药阿米替林的电子束辐照降解行为[J]. 上海大学学报(自然科学版), 2019 , 25(6) : 933 -942 . DOI: 10.12066/j.issn.1007-2861.1955
Antidepressants are an important part of pharmaceutical contaminants that are new pollutants becoming potential threat to the environment. The existing sewage treatment techniques can hardly treat them effectively. This study focuses on the application of electron beam irradiation to degradation of antidepressant amitriptyline (AMI). The influencing factors include initial concentration, irradiation dose, pH, amount of H$_{2}$O$_{2}$, various atmosphere conditions and different ions. The degradation behavior of AMI in real water environment was simulated, and possible degradation paths were proposed according to the product analysis. The above mentioned factors have shown important influences on the irradiation degradation of AMI. Degradation of target AMI obeyed the pseudo first-order kinetic equation. When the dose of irradiation was 5 kGy, the target pollutant was completely degraded, meaning that electron beam irradiation is an effective means to treat wastewater containing AMI.
Key words： antidepressant; amitriptyline; electron beam irradiation; degradation
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