研究论文

激光诱导碳纳米笼对细菌的杀伤作用

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  • 同济大学 生命科学与技术学院, 上海 200092

收稿日期: 2017-06-15

  网络出版日期: 2019-09-04

基金资助

国家自然科学基金资助项目(31370961)

Killing bacteria effect of graphic carbon nanocages under laser irradiation

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  • School of Life Science and Technology, Tongji University, Shanghai 200092, China

Received date: 2017-06-15

  Online published: 2019-09-04

摘要

以羰基铁为前驱体合成了由石墨壳层构成的石墨化碳纳米笼(graphic carbon nano- cages, GCNCs). 在671 nm激光照射下, 该GCNCs迅速将光能转化为热能. 0.1 mg/mL 的GCNCs在低功率密度的671 nm激光照射15 min的情况下, 可将大肠杆菌杀灭, 而单独激光照射不会影响细菌活性. 由于GCNCs的内部空腔可装载药物, 因此在多模式杀菌领域, GCNCs将会是一种性能优异的新型载体.

本文引用格式

韩春哲, 郭昱良, 陈杨, 桂馨 . 激光诱导碳纳米笼对细菌的杀伤作用[J]. 上海大学学报(自然科学版), 2019 , 25(4) : 597 -603 . DOI: 10.12066/j.issn.1007-2861.1953

Abstract

Graphic carbon nanocages (GCNCs) are composed of graphite shells synthesized from carbonyl iron as precursors. The GCNCs could rapidly convert laser light energy to heat under 671 nm laser irradiation. $\textit{E. coli}$ incubated with 0.1 mg/mL of GCNCs were completely killed after 15 min of 671 nm laser irradiation, while the growth of $\textit{E. coli}$ was not affected by the GCNCs without laser irradiation. As GCNCs have huge internal cavity for loading drugs, these nanomaterials may be excellent carriers for multimodal bacteria killing.

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