上海大学学报(自然科学版) ›› 2023, Vol. 29 ›› Issue (2): 200-.doi: 10.12066/j.issn.1007-2861.2475

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维生素 E 稳定型高交联聚乙烯人工膝关节磨屑的分离提取

郑 晔, 黄秀玲, 冯 景, 朱俊俊, 华子恺   

  1. 上海大学 机电工程与自动化学院, 上海 200444
  • 收稿日期:2023-03-07 出版日期:2023-04-30 发布日期:2023-04-30
  • 通讯作者: 华子恺 (1983—), 男, 副研究员, 博士, 研究方向为转化医学工程. E-mail: zikai hua@shu.edu.cn
  • 基金资助:
    国家自然科学基金青年基金资助项目 (62203287)

Separation and extraction of wear debris of vitamin E-stabilized high cross-linked polyethylene artificial knee joints

ZHENG Ye, HUANG Xiuling, FENG Jing, ZHU Junjun, HUA Zikai   

  1. School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
  • Received:2023-03-07 Online:2023-04-30 Published:2023-04-30

摘要: 维生素 E 稳定型高交联聚乙烯 (vitamin E stabilized highly cross-linked polyethy-lene, VE/HXLPE) 是一种抗氧化、低磨损的材料, 该材料磨屑是否可以用现有标准方法提取还未知. 基于标准, 采用酸消化法降解体外磨损实验中的润滑介质, 通过设置不同的消化液取样量指标, 探究其对磨屑数量、体积、形貌特征的影响. 结果表明, 改变磨屑提取方法中的取样量会影响提取的磨屑数量、体积及形貌分布. 采用现行标准提取到的磨屑 VE/HXLPE 较少, 难以达到表征数量, 而增加消化液取样量可有效改善这一问题, 更适用于提取低磨损的VE/HXLPE 磨屑.

关键词: 人工膝关节, 维生素 E 稳定型高交联聚乙烯, 磨屑提取

Abstract: Vitamin E stabilized highly cross-linked polyethylene (VE/HXLPE) is a antiox-idant material with low wear, and it is unknown whether the wear debris of this material can be extracted by the existing standard methods. Based on standard, this paper used acid digestion method to degrade the calf serum protein in vitro wear test, and set different sampling volume of the digestive fluid to explore its influence on the characteristics of the wear debris. The results show that changing the sampling volume in the extraction method will affect the quantity, volume and morphology distribution of the extracted debris. The quantity of VE/HXLPE wear debris extracted by the existing standard is small, and it is difficult to achieve the characterized quantity. Increasing the sampling volume of digestive fluid can effectively improve this problem, which is more suitable for extracting low-wear VE/HXLPE wear debris.

Key words: arti?cial knee joints, vitamin E stabilized highly cross-linked polyethylene, debris isolation

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